Hyperbaric oxygen Therapy: Mechanisms of Action
1. Hyperoxygenation: The delivery of
100% oxygen under pressure (1.5 to 3 ATA) within the hyperbaric chamber
provides up to 20 times normal oxygen to all tissues within the body. This
oxygen supersaturation is in marked contrast to breathing room air (21% oxygen
at 1 ATA).
2. Direct Pressure to Oxygen Molecules: Inside the
hyperbaric chamber, oxygen molecules are compressed and become more soluble,
obeying the scientific principles of Boyle’s Universal Gas Law. This phenomenon
allows oxygen to effortlessly cross cell membranes and enter all of the body’s
fluid systems, including plasma, synovial, lymphatic, interstitial (between
cells) and cerebrospinal fluids. Normally, only the red blood cells are capable
of transporting oxygen throughout the body. Now, all body fluids combine to
provide alternate transport routes for extra oxygen and cumulatively can
provide up to 20 times normal O2.
3. Bactericidal Ammunition – Aids in Killing
Bacteria: Conditions created within the hyperbaric
oxygen chamber are not favorable for the viability of bacteria, fungi and
viruses – organisms that cannot survive in an oxygen rich environment. Extra
oxygen is provided to the white blood cells (leukocytes) which become
supercharged in the battle against bacteria responsible for causing infection
and illness.
4. Angiogenesis – The Formation of New Blood
Vessels: Hyperbaric Oxygen stimulates the body to grow new capillaries
(angiogenesis), essentially building a new collateral circulatory system to
serve injured and healthy tissues alike. The resulting neovascularization is
extremely helpful for reaching tissues and organs that have restricted blood
flow (ischemic areas) as well as areas of the body that are lacking or
compromised in available oxygen (hypoxic areas).
5. Superoxide Dismutase (SOD) Stimulation – A
Surge of Antioxidant Capabilities: Superoxide
Dismutase (SOD) is an important enzyme found in human cells that inactivates
superoxides, the most common free radicals in the body, responsible for
destruction of cells. Hyperbaric Oxygen stimulates SOD production thereby
helping the body to rid itself of the byproducts of inflammation and damaging
free radicals.
6. Synergy With Antibiotics: Hyperbaric Oxygen has
been proven to create a synergistic effect when administered in conjunction
with certain antibiotics. Synergy can be understood as two or more agents
working together to produce a result not obtainable by any of the agents
independently. Administration of HBOT biomechanically potentiates the
effectiveness of antibiotic therapy. The capabilities of sulfanomides are
increased up to ten fold when HBOT is added. Increased oxygen levels from HBOT
alone also act as antibiotics by impairing bacterial metabolism.
7. Improves Osteoblast and Osteoclast Production: Faster
regeneration of bone is derived by hyperbaric oxygen’s ability to stimulate and
increase production of specialized cells (osteoblasts and osteoclasts)
responsible for bone repair and formation.
8. Increases Fibroblast and Collagen Production: These essential building blocks of connective-tissue, tendon and
skin matrix (fibroblasts and collagen) provide the structural framework
throughout the body and play a critical role in wound healing. Fibroblast and
collagen reproduction and growth are aided by the added availability of
increased oxygen provided during hyperbaric conditions.
9. Decreases Inflammation: Inflammation, one of the most common mechanisms of disease
and injury, is caused by biochemical byproducts that are manufactured by the body’s
natural immune response. Hyperbaric oxygen markedly decreases inflammation by
stimulating the body’s own anti-inflammatory defenses. This may be the single
most important function of HBOT.
Ask us
for Hyperbaric Oxygen Therapy Chamber
specifications and prices.
Bird Medical Devices, Mumbai, India.
Tel:91-22-65 655 123 Mobile:
91-9769 484 123 (or) 91-9769 006 123
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